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Design and fabrication of accommodating fluidic intraocular lens

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The space inside the device may be filled with optically transparent fluid or gel...

The space inside the device may be filled with optically transparent fluid or gel having an index of refraction greater than the index of vitreous humor.

The device may be such designed so that the focusing power of the lens can be changed by the deformation of the capsular bag, which may be subsequently controlled by a ciliary muscle.bonding a second optical membrane and the hollow support ring, wherein the bonded first optical membrane, the hollow support ring and the second optical membrane form a lens chamber, wherein one or more surface areas of the hollow support ring include one or more holes that allow fluid to pass between the reservoir and the lens or more pathways between the reservoir and the lens chamber to enable exchange of fluid between the lens chamber and the reservoir, wherein the fluid is at least partially transparent to visible light and has a refractive index greater than 1.33; and, wherein the said membrane is made of Polydimethylsiloxane (PDMS), wherein the fluid is an optical gel or polyphenyl ether and has a density no greater than 1.25 grams/cm3, and wherein a circular portion of the lens chamber measures at least 5 mm in diameter.

The invention of intraocular lens (IOL), a substitute for crystalline lens, represents a major advancement in cataract surgery.

After about sixty years of IOL development, one key remaining problem is its limited accommodation range compared with natural eyes.

To overcome this performance limit, we explore bio-inspired fluidic IOL.

design and fabrication of accommodating fluidic intraocular lens-54design and fabrication of accommodating fluidic intraocular lens-34design and fabrication of accommodating fluidic intraocular lens-90

An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. Because the imaging distance is fixed, presbyopia typically entails the need for bi-focals to facilitate near and far vision. 4,816,031 to Pfoff discloses an IOL with a hard PMMA lens separated by a single chamber from a flexible thin lens layer that uses microfluid pumps to vary a volume of fluid between the PMMA lens portion and the thin layer portion and provide accommodation. In view of the foregoing, it would be desirable to provide apparatus and methods that restore appropriate optical focusing power action to the human eye.

Yifan Li ; Runling Peng ; Shuilan Hu ; Maowei Wei and Jiabi Chen" Introduction to the development of intraocular lens ", Proc.

SPIE 8908, International Symposium on Photoelectronic Detection and Imaging 2013: Imaging Sensors and Applications, 89081J (August 21, 2013); doi:10.1117/12.2034088; is an access management service that provides single sign-on to protected resources.

Fluid-filled haptics disposed in fluid communication with the space vary the fluid volume in the space responsive to forces applied by the... Apart from age-related loss of accommodation ability, such loss is innate to the placement of IOLs for the treatment of cataracts. It further would be desirable to provide methods and apparatus wherein a dynamic lens surface may be effectively manipulated by the ciliary muscular mechanisms within the eye.

An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. IOLs are generally single element lenses made from a suitable polymer material, such as acrylics or silicones. It still further would be desirable to provide methods and apparatus that utilize pressure applied by the accommodating muscular action to deform an optical surface of the IOL.