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Benzodiazepines are very effective at quickly reducing the symptoms of anxiety and agitation that occur in a manic or hypomanic episode (high mood).

They can only be used for short periods of time because they can cause dependence (addiction).

I was taught in my Emergency Medicine residency that the benzos were “minor sedatives” and the antipsychotics were “major sedatives.” However, there have been several studies comparing the two when sedating agitated patients, including this 2010 Cochrane Review, and, in fact, both work well. Each has advantages and disadvantages that should be considered.

Antipsychotics for Sedation–Haloperidol The best overall antipsychotic for rapid sedation of agitated patients in a correctional setting, in my opinion, is good, old haloperidol. The main advantage of haloperidol is that it is so safe.

Haldol has been safely used for this indication (probably) millions of times world-wide. It does not cause respiratory depression and so can be given to intoxicated patients. This means that it can safely be given to patients who are already taking antipsychotics.

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An anti-anxiety or a sleeping pill taken the night before the appointment, an hour before going to bed, can help with falling asleep and getting some rest.It’s easy to become disorientated and miss your stop if going by bus or train, or walk straight in front of a car – or you might even forget that you’re on your way to your dentist’s (“hey cool” I hear you say :wink:)… The classification of whether a benzodiazepine is sedative-hypnotic or anti-anxiety is to some extent an arbitrary one, as the boundaries are quite fluid.As a rule of thumb, in higher doses benzos act like sedatives and may promote sleep, while in lower doses, they simply reduce anxiety.This can lead to withdrawal symptoms if these medicines are taken regularly for longer than a couple of weeks.In these cases, the benzodiazepine should be withdrawn very gradually rather than being stopped abruptly, to prevent withdrawal symptoms.All of a sudden they begin experiencing withdrawal symptoms, a telltale sign of addiction.